This high-density chondroitin sulfate is formulated with a bulk density of ≥0.75 g/ml, compared with ≥0.50 g/ml for conventional chondroitin sulfate. Its larger granules and higher density improve handling characteristics, enable efficient formulation processes, and support more compact product designs in capsules, tablets, and powder blends. For commercial procurement teams, these properties translate directly into reduced packaging volume, improved production line throughput, and consistent fill weights across manufacturing runs.
Production follows HACCP and ISO quality management protocols. Each batch receives a Certificate of Analysis (COA), and full technical documentation including TDS and MSDS is available upon request. The material complies with USP and EP standards, with infrared identification verified against USP Chondroitin Sulfate Sodium RS reference standards.
Test Items | Specifications |
|---|---|
Appearance | White or almost white granule, hygroscopic |
Solubility | Freely soluble in water, practically insoluble in acetone and in ethanol 96% |
Infrared Identification | The infrared absorption spectrum is consistent with that obtained with USP Chondroitin Sulfate Sodium RS |
Sodium Identification | Positive |
Assay by CPC (dry basis) | 90.0-105.0% |
Clarity and Color | <0.35 at 420nm |
Limit of protein | ≤6.0% |
Specific Rotation | -20.0° - -30.0° |
pH | 5.5-7.5 |
Heavy Metals | ≤20ppm |
Residue on Ignition | 20.0-30.0% |
Loss on Drying | <12.0% |
Chlorides | <0.50% |
Sulfate | <0.24% |
Electrophoretic Purity | ≤2% |
Limit of Nonspecific Dissaccharides | ≤10.0% |
Residual Solvents | ≤0.5% |
Bulk Density | ≥0.75g/ml |
Particle Size | 100% thru 40 Mesh or customize |
Total Plate Count | ≤1000 CFU/g |
Yeast and Mold | ≤100 CFU/g |
E. Coli | Negative |
Salmonella | Negative |
S. aureus | Negative |
P. aeruginosa | Negative |
Assay by CPC (dry basis) ranges from 90.0% to 105.0%, ensuring consistent potency across production batches. Electrophoretic purity is maintained at ≤2%, and nonspecific disaccharides are limited to ≤10.0%. These specifications support predictable formulation outcomes for bone health supplement manufacturers.
Particle size specifications are available at 100% through 80 mesh, with custom particle sizes available upon request. Packaging and product form options can be tailored to match specific business operations and production line requirements.
The material is produced under GMP conditions and holds HALAL certification. Heavy metal content is controlled at ≤20ppm, and residual solvents are maintained at ≤0.5%. Microbiological testing covers total plate count, yeast and mold, and four pathogen indicators: E. Coli, Salmonella, S. aureus, and P. aeruginosa, all meeting specified limits.
This high-density chondroitin sulfate is suitable for joint health dietary supplements in multiple dosage forms, including tablets, capsules, powders, and liquids. Its improved flow properties contribute to consistent capsule filling and uniform tablet weight distribution during manufacturing.
The ingredient works effectively in combined formulas with glucosamine, MSM, collagen, and other joint support components. The higher bulk density allows for more active ingredient per capsule, enabling more potent finished product formulations without increasing capsule size.
High-density chondroitin sulfate has a minimum bulk density of 0.75 g/ml, while conventional chondroitin sulfate typically measures ≥0.50 g/ml. This 50 percent increase in density reduces capsule fill volume by up to 30 percent and improves flow characteristics during production.
Yes, particle size specifications can be adjusted beyond the standard 100% through 80 mesh. Packaging options and product form can also be tailored to align with specific production requirements and business operations.
Each batch is accompanied by a Certificate of Analysis (COA). Additional documentation including Technical Data Sheet (TDS) and Material Safety Data Sheet (MSDS) is available upon request. Production follows ISO, HACCP, and GMP standards, with compliance to USP and EP monographs.
With standardized assay content of 90.0-105.0% and controlled purity parameters, this chondroitin sulfate provides consistent active ingredient levels for bone health supplement formulations. Its high-density property allows formulators to achieve higher loading per dosage unit, supporting more concentrated joint health products.
