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Food-Grade Chondroitin Sulfate for Supplement Brand Formulation
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Food-Grade Chondroitin Sulfate for Supplement Brand Formulation

Product Name: Chondroitin Sulfate
CAS Number: 9007-28-7
Molecular Formula: (C₁₄H₂₁NO₁₄S)ₙ
Appearance: White to Off-white Powder
Source: Bovine Cartilage /Avian Cartilage/ Shark Cartilage/Porcine Cartilage
Grade: USP / EP / Food Grade
Assay: 90%, 95%, 98%
Packaging: 25 kg Fiber Drum  (Double PE Bags Inside)
Shelf Life: 24 Months
Storage: Store in a cool, dry place. Keep the container tightly closed and protect it from direct sunlight and moisture.
Availability:
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Chondroitin Sulfate is a naturally occurring glycosaminoglycan (GAG) derived from animal cartilage. As a key structural component of cartilage, it helps maintain the integrity of the cartilage matrix and supports normal joint function. The product is a white to off-white hygroscopic powder that is freely soluble in water and practically insoluble in acetone and ethanol.

chondroitin sulfate
Chondroitin Sulfate Manufacturer

As a leading chondroitin sulfate manufacturer, we provide a comprehensive range of sources including bovine, porcine, shark, and avian, plus specialty variants like low molecular weight and high density grades. All products meet USP and EP standards, produced under ISO, GMP, and HACCP quality systems with full traceability. With over 20 years of global export expertise and complete documentation support, we serve as a trusted one-stop partner for nutraceutical and functional food brands worldwide.

Primary Sources and Variants

Variant

Source

Key Characteristics

Bovine

Cattle cartilage

Widely used, cost-effective, compatible with Glucosamine and MSM

Avian

Poultry cartilage

Premium source, favorable bioavailability profile

Shark

Marine cartilage

Suitable for marine collagen blend formulations

Porcine

Pig cartilage

Stable supply chain, consistent batch quality

Halal

Certified Halal source

Compliant with religious and international export requirements

Low Molecular Weight

Processed form

Enhanced solubility and absorption characteristics

High Bulk Density

Specially processed

Optimized flow properties for automated production lines

Chondroitin Sulfate Specifications and Quality Parameters

Test Items

Specifications

Appearance

White or almost white powder, hygroscopic powder

Solubility

Freely soluble in water, practically insoluble in acetone and in ethanol 96%

Infrared Identification

The infrared absorption spectrum is consistent with that obtained with USP Chondroitin Sulfate Sodium RS

Sodium Identification

Positive

Assay by CPC (dry basis)

90.0-105.0%

Clarity and Color

<0.35 at 420nm

Limit of protein

≤6.0%

Specific Rotation

-20.0° - -30.0°

pH

5.5-7.5

Heavy Metals

≤20ppm

Residue on Ignition

20.0-30.0%

Loss on Drying

<12.0%

Chlorides

<0.50%

Sulfate

<0.24%

Electrophoretic Purity

≤2%

Limit of Nonspecific Dissaccharides

≤10.0%

Residual Solvents

≤0.5%

Bulk Density

≥0.60g/ml

Particle Size

100% thru 80 Mesh or customize

Total Plate Count

≤1000 CFU/g

Yeast and Mold

≤100 CFU/g

E. Coli

Negative

Salmonella

Negative

S. aureus

Negative

P. aeruginosa

Negative

Chondroitin Sulfate Applications in Commercial Formulations

Joint Health Supplement Formulations

Chondroitin sulfate serves as a foundational ingredient in joint health products, including tablets, capsules, and powder blends. It is commonly incorporated into daily supplement regimens targeting adult populations seeking joint structure support and maintenance of joint flexibility.

Sports Nutrition Product Integration

Sports nutrition brands include chondroitin sulfate in formulations designed for active individuals. The ingredient supports cartilage maintenance in users with regular physical activity, making it suitable for pre-workout, post-workout, and daily wellness product lines.

Combined Ingredient Compatibility

Chondroitin sulfate demonstrates compatibility with several other active ingredients commonly used in joint health formulations. It can be combined with glucosamine, MSM, collagen peptides, and hyaluronic acid to create multi-component joint support products.

Manufacturing Standards and Certifications

Quality Control Protocols

Each batch of chondroitin sulfate undergoes testing using CPC and HPLC methods to verify assay content. The production process includes multiple purification steps to control impurity levels, including heavy metals, residual solvents, and microbial contaminants. Batch-to-batch consistency is maintained through standardized extraction and drying procedures.

Compliance and Certification Overview

Production facilities operate under ISO-certified quality management systems and follow GMP manufacturing practices. Products conform to USP and EP pharmacopeial standards. Halal and Kosher certifications are available for applicable product variants. Full traceability is maintained from raw material sourcing through finished product packaging.

Packaging and Supply Capabilities

Standard Packaging Specifications

Standard packaging consists of 25 kg fiber drums with double PE inner bags to protect product integrity during storage and transit. Custom packaging options are available to accommodate specific commercial procurement requirements, including different drum sizes, bag-in-box configurations, and private labeling arrangements.

Bulk Production and Lead Times

Direct factory supply supports bulk order volumes for enterprise customers. Production capacity accommodates both regular scheduled orders and urgent replenishment requests. With over 20 years of international export experience, we provide complete documentation support including batch-specific COA, TDS, and MSDS, along with logistics coordination for global shipments.

Production Workshop
Extraction Workshop
Quality Control Lab

FAQ About Chondroitin Sulfate Sourcing

What chondroitin sulfate sources are available for commercial production?

We offer seven product variants sourced from bovine, avian, shark, and porcine cartilage. Specialty variants include Halal-certified, low molecular weight, and high bulk density grades to suit different formulation needs and production processes.

How is chondroitin sulfate purity measured and verified?

Purity is determined through assay testing using the CPC method on a dry basis, with specifications ranging from 90.0% to 105.0%. Additional purity indicators include electrophoretic purity (≤2%) and limits for nonspecific disaccharides (≤10.0%). Each batch is tested and documented with a certificate of analysis.

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