Acetylated Sodium Hyaluronate (INCI: Sodium Acetylated Hyaluronate) is a modified form of hyaluronic acid produced through acetylation technology. This molecular modification enhances skin affinity, allowing the ingredient to adhere to the skin surface and provide extended moisture retention compared to conventional sodium hyaluronate. With ≥95.0% purity and cosmetic-grade quality verified by heavy metal and microbial testing, it supports the formulation of premium serums, creams, and anti-aging products. Manufactured under GMP conditions and supported by dedicated technical services, this ingredient serves cosmetic brands and formulation teams worldwide.
The acetyl groups introduced during modification help the ingredient maintain contact with the skin surface for extended periods. This prolonged residence time translates to sustained moisture delivery, supporting formulations designed for all-day hydration.
Acetylated HA demonstrates higher skin adhesion compared to standard hyaluronic acid. This property allows the ingredient to remain on the skin surface rather than being easily removed, contributing to consistent product performance after application.
By supporting moisture retention at the skin surface, acetylated sodium hyaluronate contributes to the maintenance of skin barrier function. This makes it suitable for repair-focused and protective skincare formulations.
The ingredient imparts a silky, smooth skin feel when incorporated into cosmetic products. It also exhibits higher stability than conventional HA, providing formulators with greater flexibility in product development and shelf-life planning.
The following comparison summarizes the performance differences relevant to formulation design:
Feature | Acetylated HA | Regular HA |
|---|---|---|
Skin Affinity | Very High⭐⭐⭐⭐⭐ | Moderate⭐⭐⭐ |
Hydration Duration | Long-lasting | Short-term |
Stability | High | Normal |
Moisture Retention | Enhanced | Standard |
These differences make acetylated sodium hyaluronate suitable for premium skincare products requiring sustained performance and elevated sensory experience.
Test Items | Requirements |
|---|---|
Appearance | White powder or granules |
Identification (IR) | The infrared absorption spectrum of the sample should be consistent with the reference spectrum |
Sodium Identification | Should show a positive reaction for sodium salts |
Odor | Odorless |
Glucuronic Acid | ≥ 45.0% |
Sodium Hyaluronate Content | ≥ 95.0% |
Acetyl content (%) | 23.0-29.0 |
Average Molecular Weight | Measured values (customizable) |
Intrinsic Viscosity | Measured values |
Kinematic Viscosity | Measured values |
Absorbance (280 nm) | ≤ 0.25 |
Transparency | ≥ 99.0% |
Loss on Drying | ≤ 10.0% |
pH (1% solution) | 6.0 – 8.0 |
Protein Content | ≤ 0.10% |
Ash Content | ≤ 13.0% |
Physical Properties | |
Particle Size | 80 mesh (customizable) |
Bulk Density | Measured values |
Heavy Metals | |
Heavy Metals (as Pb) | ≤ 10 mg/kg |
Lead (Pb) | ≤ 1 mg/kg |
Arsenic (As) | ≤ 2 mg/kg |
Mercury (Hg) | ≤ 0.1 mg/kg |
Chromium (Cr) | ≤ 1 mg/kg |
Microbiological | |
Total Plate Count | ≤ 100 CFU/g |
Yeast × Mold | ≤ 50 CFU/g |
Staphylococcus aureus | Negative |
Pseudomonas aeruginosa | Negative |
Hemolytic Streptococcus | Negative |
This ingredient is suitable for inclusion in various cosmetic product types:
High-end facial serums
Anti-aging skincare products
Moisturizing creams
Repair formulations
Premium cosmetic products
Formulators can integrate acetylated sodium hyaluronate into products targeting mature skin, dryness concerns, or consumers seeking elevated sensory experiences.
As a hyaluronic acid specialist manufacturer, we offer a complete portfolio including oligomeric, crosslinked, and acetylated HA variants. Production follows standardized processes to support batch-to-batch consistency, which is relevant for commercial procurement and ongoing product manufacturing.
The product is available for global shipment. Pricing structures are designed to align with volume requirements of enterprise customers and formulation brands.
Technical support is available to assist with formulation integration, compatibility testing, and product selection guidance. This service supports R&D teams and production units during product development and scale-up phases.
The standard product has a sodium hyaluronate content of ≥95.0%. Additional purity parameters including glucuronic acid content, protein content, and absorbance values are specified in the product specification sheet.
Yes, average molecular weight and particle size (standard 80 mesh) are customizable parameters. Specific requirements can be discussed for industrial applications and volume orders.
The acetyl content ranges from 23.0% to 29.0%. This range is controlled during the acetylation process to ensure consistent performance across batches.
Yes, acetylated sodium hyaluronate is designed for cosmetic use and is commonly incorporated into anti-aging serums, moisturizing creams, and premium skincare products. Its enhanced skin affinity and long-lasting hydration properties support anti-aging formulation objectives.
Each batch undergoes testing for appearance, purity parameters, heavy metal content, and microbiological indicators. The specification sheet provides complete test items and their corresponding acceptance criteria.
Acetylated HA is produced by introducing acetyl groups to the hyaluronic acid molecule. This modification increases skin affinity, extends hydration duration, and improves stability compared to conventional sodium hyaluronate.
