4D Multi-Molecular Sodium Hyaluronate Solution is a synergistic complex composed of four molecular weights of hyaluronic acid, formulated for commercial skincare production. This multi-molecular system delivers hydration across multiple skin layers simultaneously, from surface film formation to deep dermal penetration.
Manufactured in an ISO22000 and GMP-certified facility in Shandong, China, this solution maintains ≥99% transparency and controlled protein content ≤0.10% across production batches, supporting consistent formulation outcomes for enterprise customers.
The "4D" designation refers to hydration activity across four skin layers:
Surface hydration: Forms a moisture-retaining film on the skin surface
Epidermal moisture retention: Supports water retention within the epidermal layer
Deep skin penetration: Reaches deeper skin layers through lower molecular weight fractions
Long-lasting moisture release: Provides sustained hydration through staggered molecular absorption rates
The 4D formulation combines ultra-low, low, medium, and high molecular weight sodium hyaluronate fractions. Each molecular weight range contributes to a different layer of skin interaction, creating a full-spectrum moisturizing profile compared to single-molecular weight alternatives.
Function | Description |
|---|---|
Deep Hydration | Penetrates into deeper skin layers |
Surface Protection | Forms a moisture-retaining film |
Long-Lasting Effect | Sustained hydration profile |
Skin Repair Support | Improves elasticity and smoothness |
Additional formulation characteristics include enhanced compatibility with various skincare bases, making this ingredient suitable for integration into existing product lines without major reformulation adjustments.
Test Items | Requirements |
|---|---|
Appearance | White powder or granules |
Identification (IR) | The infrared absorption spectrum of the sample should be consistent with the reference spectrum |
Sodium Identification | Should show a positive reaction for sodium salts |
Odor | Odorless |
Intrinsic Viscosity | Measured values |
Kinematic Viscosity | Measured values |
Absorbance (280 nm) | ≤ 0.25 |
Transparency | ≥ 99.0% |
Loss on Drying | ≤ 10.0% |
pH (1% solution) | 6.0 – 8.0 |
Protein Content | ≤ 0.10% |
Ash Content | ≤ 13.0% |
Physical Properties | |
Particle Size | 80 mesh (customizable) |
Bulk Density | Measured values |
Heavy Metals | |
Heavy Metals (as Pb) | ≤ 10 mg/kg |
Lead (Pb) | ≤ 1 mg/kg |
Arsenic (As) | ≤ 2 mg/kg |
Mercury (Hg) | ≤ 0.1 mg/kg |
Chromium (Cr) | ≤ 1 mg/kg |
Microbiological | |
Total Plate Count | ≤ 100 CFU/g |
Yeast & Mold | ≤ 50 CFU/g |
Staphylococcus aureus | Negative |
Pseudomonas aeruginosa | Negative |
Hemolytic Streptococcus | Negative |
4D Multi-Molecular Sodium Hyaluronate Solution is used in the formulation of premium serums, moisturizers, and anti-aging products. It is suitable for wholesale brands, private label lines, and contract manufacturing operations that require consistent, specification-defined cosmetic ingredients.
Formulators working with this ingredient can reference the pH range of 6.0–8.0 and the ≥99% transparency specification when developing clear gel formulations, serums, and aqueous-based skincare products.
Production takes place in a facility certified under ISO22000 and GMP standards. Each batch is tested against the full specification panel listed above, including heavy metal screening and microbiological testing. The controlled protein content (≤0.10%) supports formulation stability and reduces the risk of sensory changes in finished products.
Single-molecular weight hyaluronic acid primarily interacts with one skin layer, depending on its molecular size. 4D Multi-Molecular Sodium Hyaluronate combines four molecular weight ranges, allowing hydration activity across surface, epidermal, and deeper skin layers in a single ingredient.
This ingredient is compatible with serums, moisturizers, gels, toners, and anti-aging product bases. Its pH range of 6.0–8.0 aligns with most standard skincare formulation parameters.
The product is manufactured in an ISO22000 and GMP-certified facility and meets the specification parameters listed in the table above, including heavy metal limits and microbiological criteria suitable for cosmetic applications.
