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The role of sodium hyaluronate? Moisturizing effect is the most important role of sodium hyaluronate in cosmetics. Compared with other moisturizers, the relative humidity of the surrounding environment has little effect on its moisturizing effect. The moisturizers commonly used in cosmetics include glycerol, propylene glycol, sorbitol, polyethylene glycol, sodium lactate, pyrrolidone carboxylate, etc. Compared with these humectants, sodium hyaluronate has the highest moisture absorption at low relative humidity (33%) and the lowest moisture absorption at high relative humidity (75%). This unique property is suitable for the moisturizing effect of cosmetics in different seasons and different environmental humidity, such as dry winter and wet summer. The moisture retention of sodium hyaluronate is related to its Mr. the higher the MR, the better the moisture retention. Sodium hyaluronate is rarely used alone as a moisturizer and is often used in combination with other moisturizers. Sodium hyaluronate is an inherent biological substance of skin, and exogenous sodium hyaluronate is a supplement to endogenous ha of skin. Sodium hyaluronate can penetrate into the skin epidermis, promote the supply of skin nutrition and waste excretion, so as to prevent skin aging and play the role of beauty and beauty. Skin care is more important than other make-up, which has become a modern sense of beauty. Repair and prevention of skin damage. Skin burns or sunburn caused by sun exposure, such as redness, blackening and peeling, are mainly caused by ultraviolet rays in the sun. Sodium hyaluronate can promote the regeneration of injured skin by promoting the proliferation and differentiation of epidermal cells and scavenging oxygen free radicals. Prior use also has a certain preventive effect. Its action mechanism is different from that of UV absorbers commonly used in sunscreen. Therefore, HA and UV absorbers are used together in sunscreen and skin care products, which can simultaneously reduce the transmission of UV and repair the skin damage caused by a small amount of UV, playing a dual protective role. The combination of sodium hyaluronate, EGF and heparin can accelerate the regeneration of epidermal cells and make the skin tender, smooth and elastic. When the skin is slightly burned, applying aqueous cosmetics containing sodium hyaluronate on the surface can reduce pain and accelerate the healing of the injured skin. Lubricity and film-forming property: sodium hyaluronate is a high molecular polymer with strong lubricity and film-forming property. Skin care products containing sodium hyaluronate have obvious lubrication and good hand feel when applied. After being applied to the skin, a film can be formed on the skin surface to make the skin feel smooth and moist, and protect the skin. Hair care products containing HA can form a film on the hair surface, which can moisturize, lubricate, protect hair and eliminate static electricity, making the hair easy to comb, elegant and natural. Thickening, sodium hyaluronate has high viscosity in aqueous solution, 1% of its aqueous solution is gelatinous, and it can play a thickening and stabilizing role in cosmetics....
Chondroitin sulfate (CS, hereinafter referred to as CS) is a kind of sulfated glycosaminoglycans, which exists in human and animal connective tissues. It is mainly distributed in cartilage, bone, tendon, sarcolemma and vascular wall. D-glucuronic acid and N-acetyl-D-galactosamine are connected by 1,3 glycosidic bonds to form disaccharides β- 1 and 4 glycosidic bonds are connected, and the relative molecular weight is generally 25000 ~ 30000. According to the types of uronic acid in its molecular structure and the position of sulfate on aminohexose, it is mainly divided into chondroitin sulfate A (CS-A), chondroitin sulfate C (CS-C), chondroitin sulfate D (cs-d), chondroitin sulfate e (CS-E), etc. In Europe, the United States, Japan and other countries, CS is mainly used as health food or medicine for the prevention and treatment of cardiovascular and cerebrovascular diseases, osteoarthritis (OA), neuroprotection, etc. In recent years, with more extensive research on the pharmacological effect and application of CS, some new effects and mechanisms have been found, and its wider application in disease prevention and treatment has also been discussed. The CS we use now is a kind of natural acidic mucopolysaccharide from animal cartilage (because of its viscosity - glycosaminoglycan (glycosaminoglycan is the representative component of animal proteoglycan and exists in the form of proteoglycan in cartilage). The types of chondroitin sulfate in different animals are different. The bones of pigs, cattle and sheep mainly contain chondroitin sulfate a, Cartilage of sharks, squid and other marine animals mainly contains chondroitin sulfate C. The role of sulfated cartilage in the treatment of osteoarthritis: CS can reduce the pain of patients with osteoarthritis (OA), improve joint function, reduce joint swelling and effusion, and prevent the gap narrowing of knee and hand joints. CS can alleviate the symptoms of OA (significantly reduce pain, shorten morning stiffness, increase grip strength and significantly improve function), and reduce the dosage of non steroid anti-inflammatory drugs (NSAIDs). Compared with NSAIDs, CS has lower cost and better gastrointestinal tolerance in the treatment of OA -- when using NSAIDs, 2666 gastrointestinal adverse events (including 90 serious adverse events) occurred per 10000 patients, and CS was basically non-toxic and side effects. CS has been listed as a slow acting drug to change the symptoms and condition of OA and an OA disease improvement drug in clinical application. Others: such as adhesion regulation, mucosal protection, anti adhesion, promoting cell proliferation, inhibiting angiogenesis, treating corneal injury and protecting cornea, anti-virus, etc. Chondroitin sulfate is widely found in human and animal cartilage. Its medicinal preparation mainly contains two isomers of chondroitin sulfate A and chondroitin sulfate C. The content of chondroitin sulfate in cartilage of animals of different varieties and ages is different. Its pharmacological effects are as follows: chondroitin sulfate can clear the lipids and lipoproteins in the blood, clear the cholesterol of blood vessels around the heart, prevent atherosclerosis, and increase the conversion rate of lipids and fatty acids in cells. Chondroitin sulfate can effectively prevent and treat coronary heart disease. It has anti atherosclerotic and anti atherogenic plaque effects on experimental atherosclerosis model; It can increase the coronary artery division or collateral circulation of atherosclerosis, and accelerate the healing, regeneration and repair of myocardial necrosis or degeneration caused by experimental coronary atherosclerosis or embolism. It can increase the biosynthesis of messenger RNA (mRNA) and deoxyribonucleic acid (DNA) and promote cell metabolism. Low anticoagulant activity. Chondroitin sulfate has mild anticoagulant effect. Each LMG of chondroitin sulfate A is equivalent to the anticoagulant activity of 0.45u heparin. This anticoagulant activity does not depend on antithrombin III. it can exert anticoagulant activity through fibrinogen system. Chondroitin sulfate also has anti-inflammatory, accelerating wound healing and anti-tumor effects....
Sodium hyaluronic acid (HA), also known as sodium hyaluronate, is a natural polymer linear mucopolysaccharide repeatedly connected with D-glucuronic acid and N-acetylglucosamine as disaccharide units. It widely exists in animal tissues and body fluids, such as joint fluid, ocular vitreous body, umbilical cord, skin, etc. Sodium hyaluronate has good viscoelasticity and excellent water retention due to its unique structure, and has important physiological and biological functions. It has good histocompatibility and non immunogenicity. Therefore, it is widely used in clinic. For example, when sodium hyaluronate is used in ophthalmic surgery, it can protect ocular tissues; Treatment of osteoarthritis and rheumatoid arthritis; As a soft tissue filler, it can correct lacrimal sulcus deformity, abundant lip, abundant earlobe, etc; It can also be used as a drug carrier. Sodium hyaluronate is a high molecular mucopolysaccharide with strong viscoelasticity and osmotic pressure. It is a physiological active substance of human body. At present, it is widely used in various tissues of human body. It is not only the main component of joint synovial fluid, but also an important component of cartilage matrix. Sodium hyaluronate placed in the uterine cavity can be absorbed within 2 hours, so it can quickly and effectively prevent intrauterine adhesion. The mechanism of sodium hyaluronate in preventing intrauterine adhesion in hysteroscopic surgery mainly lies in its strong lubrication function, which can reduce friction, reduce the generation of blood fibrin, promote rapid wound healing, alleviate local inflammatory reaction, control bleeding, form a chemical scaffold in the intrauterine cavity, and promote the growth and differentiation of serosa cells, Then it plays the effect of physiological repair of traumatic serosa, so it has a good role in preventing adhesion. Postoperative application can repair the tissue injury caused by surgical operation, shield the pain transmission of injured tissue, and reduce the formation of scar like fibrous band of injured tissue. The total effective rate in the observation group was 88.0%, higher than 60.0% in the control group (P < 0.05); After operation, the intrauterine adhesion score in the observation group was lower than that in the control group (P < 0.05). he difference between sodium hyaluronate and hyaluronic acid. Hyaluronic acid is acid and sodium hyaluronate is salt. Sodium is more stable. Adding sodium will turn into a non-Newtonian fluid. It is very good for exfoliation. Hyaluronic acid is a holy tonic product. You should know that hyaluronic acid belongs to hyaluronic acid. Sodium hyaluronate has moisturizing effect. Hyaluronic acid is a biochemical drug with high clinical value. It is widely used in various ophthalmic operations, such as lens implantation, corneal transplantation and anti glaucoma surgery. It can also be used to treat Guan inflammation and accelerate wound healing. Sodium hyaluronate has the following functions in skin beauty and moisturizing. Moisturizing effect is the most important role of sodium hyaluronate in cosmetics. Compared with other moisturizers, sodium hyaluronate has the highest moisture absorption in low humidity environment and the lowest moisture absorption in high humidity environment. This unique property can meet the requirements of skin for moisturizing effect of cosmetics in different seasons and environmental humidity. It has nutritional effect. Sodium hyaluronate is the inherent biological substance of human body. It is the supplement of endogenous hyaluronic acid through the supplement of exogenous sodium hyaluronate. Repair and prevention. Sodium hyaluronate can promote the proliferation and differentiation of epidermal cells, remove oxygen free radicals and regenerate the damaged skin. Lubricity and film formation. After sodium hyaluronate is applied to the skin, a film can be formed on the skin surface to make the skin have a good sense of smoothness and lubrication and protect the skin. Thickening. The aqueous solution of sodium hyaluronate 1% is gelatinous, and it can play a role of thickening and stabilization in cosmetics....
With the development of science and technology, the application of electronic products is more and more widely, mobile phones, computers, television has become an indispensable part of our life. Although these electronic products have brought a lot of convenience to our life, our eyes are suffering from it. Long term use of electronic products will cause various eye diseases. When we choose drugs for treatment, we must try our best to choose safe and effective drugs. Chondroitin sulfate eye drops is a kind of medicine commonly used in the treatment of eye diseases, so today we will learn, what are the hazards of chondroitin sulfate eye drops? Chondroitin sulfate eye drops can effectively alleviate some eye diseases, but long-term use will also produce certain harm. The most common harm is the stinging sensation in the eyes. Occasionally, patients have severe symptoms such as congestion, itching, redness and swelling in the eyes. In case of such symptoms during use, the use should be stopped immediately and the doctor should be consulted. For patients with severe eye pain and glaucoma, the use must be under the guidance of the doctor. Chondroitin sulfate eye drops is suitable for keratitis, corneal ulcer, corneal injury and other symptoms. The main components of chondroitin sulfate eye drops include chondroitin sulfate, taurine, vitamin E and vitamin B6. Chondroitin sulfate has strong water holding capacity, which can protect cornea and promote corneal repair. Sulfuric acid has antibacterial and anti-inflammatory effect. Vitamin E can improve ocular microcirculation and promote the recovery of inflammatory tissue. Vitamin B6 can eliminate blurred vision caused by eye fatigue and prevent corneal dryness. Do not let bottle mouth touch hands and eyes when using eye drops. The bottle cap should be tightened immediately after use to avoid drug contamination. Chondroitin sulfate and any ingredients in the drug are strictly prohibited for patients with allergic reaction. Pregnant and lactating women should consult a doctor before use. What are the differences between chondroitin sulfate and ammonia sugar? Chondroitin sulfate and ammonia sugar are different, for those who need to apply, more attention should be paid to distinguish. In fact, glucosamine also belongs to chondroitin, because chondroitin can be divided into glucosamine chondroitin and chondroitin sulfate. Both of them are very good for our bones, but there are certain differences in application. If it is to treat joint diseases, it is more appropriate to choose glucosamine chondroitin, because chondroitin sulfate is mainly used in the treatment of neuralgia or arthralgia, but the control effect of arthritis is poor, so different problems need to choose appropriate drugs, If you don't know how to judge, then don't choose blindly, be sure to ask a regular doctor for guidance. Chondroitin sulfate is used as a hypolipidemic drug. It is mainly used to treat hyperlipidemia. Its clinical application includes the following aspects. Chondroitin sulfate is used as health food or health care medicine for long-term prevention and treatment of coronary heart disease, angina, myocardial infarction, coronary atherosclerosis, myocardial ischemia and other diseases. It has no obvious toxic and side effects, and can significantly reduce the incidence rate and mortality of patients with coronary heart disease. Long term clinical application has found that lipid deposition on artery and vein wall can be effectively removed or reduced, which can significantly reduce plasma cholesterol and prevent the formation of atherosclerosis. Chondroitin sulfate is used in the treatment of neuralgia, neurogenic migraine, arthralgia, arthritis, scapular joint pain, and pain after abdominal surgery. The prevention and treatment of hearing impairment caused by streptomycin, hearing difficulty caused by various noises and tinnitus are effective. For chronic nephritis, chronic hepatitis, keratitis and corneal ulcer and other adjuvant treatment. In recent years, it has been reported that chondroitin in shark cartilage has anti-tumor effect. In addition, chondroitin sulfate is also used in cosmetics and wound healing agents. Chondroitin sulfate is also used for eye drops....
Sodium hyaluronate is an inherent component in human body, which is a kind of glucanal acid without species specificity. It widely exists in placenta, amniotic fluid, lens, articular cartilage, skin and dermis. It belongs to hyaluronic acid with small molecule. It can improve the microcirculation and nutrient absorption of skin blood, and help maintain normal metabolism. Because of its super moisturizing properties, sodium hyaluronate can reduce wrinkles and make skin smoother and softer. Sodium hyaluronate (HA), as a recognized natural moisturizing factor, has been favored in skin care industry. It's one of the moisturizing ingredients, but the effect of sodium hyaluronate is far more than that. What effect does sodium hyaluronate have? Moisturizing effect. The most important role of sodium hyaluronate in cosmetics is moisturizing. The moisturizing property of sodium hyaluronate is closely related to its quality. The higher the quality, the better the moisturizing property. Sodium hyaluronate as a moisturizer is rarely used alone, often combined with other moisturizers. Sodium hyaluronate is an inherent biological substance of the skin. Small sodium hyaluronate can penetrate into the epidermis of the skin, promote the supply of skin nutrition and the excretion of waste, so as to prevent skin aging and play the role of beauty and beauty. Sodium hyaluronate can promote the regeneration of damaged skin by promoting the proliferation and differentiation of epidermal cells and scavenging oxygen free radicals. Pre use also has a certain preventive effect. Sodium hyaluronate has the effect of anti wrinkle. With the increase of age, the content of hyaluronic acid in the skin drops sharply, which weakens the water holding capacity of the skin, resulting in wrinkles. The small molecule of sodium hyaluronate, can penetrate into the dermis, promote blood microcirculation, is conducive to the absorption of nutrients, play an anti wrinkle role. Is sodium hyaluronate hyaluronic acid? Sodium hyaluronate is not hyaluronic acid, although the two are very similar, can play a lubricating role, but the structure is slightly different. Hyaluronic acid, scientific name hyaluronic acid, is an acid mucopolysaccharide. Sodium hyaluronate is an ingredient of skin and some tissues of the body. It has many functions. For the skin, it is the best natural moisturizing ingredient, which can keep the water in the tissue cells. This kind of maintenance will not be lost because of the amount of water around, so it is a very good moisturizer. Now many beauty products contain sodium hyaluronate, such as external use or subcutaneous injection, which is a very good moisturizer and can also be used for filling. For example, local filling, but the sodium hyaluronate injected into the skin from outside, because there is a metabolic process, generally about half a year, there is no metabolic decomposition, so repeated injection treatment is needed....
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