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Difference between sodium hyaluronate and hyaluronic acid

Sodium hyaluronic acid (HA), also known as sodium hyaluronate, is a natural polymer linear mucopolysaccharide repeatedly connected with D-glucuronic acid and N-acetylglucosamine as disaccharide units. It widely exists in animal tissues and body fluids, such as joint fluid, ocular vitreous body, umbilical cord, skin, etc. Sodium hyaluronate has good viscoelasticity and excellent water retention due to its unique structure, and has important physiological and biological functions. It has good histocompatibility and non immunogenicity. Therefore, it is widely used in clinic. For example, when sodium hyaluronate is used in ophthalmic surgery, it can protect ocular tissues; Treatment of osteoarthritis and rheumatoid arthritis; As a soft tissue filler, it can correct lacrimal sulcus deformity, abundant lip, abundant earlobe, etc; It can also be used as a drug carrier.

Sodium hyaluronate is a high molecular mucopolysaccharide with strong viscoelasticity and osmotic pressure. It is a physiological active substance of human body. At present, it is widely used in various tissues of human body. It is not only the main component of joint synovial fluid, but also an important component of cartilage matrix. Sodium hyaluronate placed in the uterine cavity can be absorbed within 2 hours, so it can quickly and effectively prevent intrauterine adhesion. The mechanism of sodium hyaluronate in preventing intrauterine adhesion in hysteroscopic surgery mainly lies in its strong lubrication function, which can reduce friction, reduce the generation of blood fibrin, promote rapid wound healing, alleviate local inflammatory reaction, control bleeding, form a chemical scaffold in the intrauterine cavity, and promote the growth and differentiation of serosa cells, Then it plays the effect of physiological repair of traumatic serosa, so it has a good role in preventing adhesion. Postoperative application can repair the tissue injury caused by surgical operation, shield the pain transmission of injured tissue, and reduce the formation of scar like fibrous band of injured tissue. The total effective rate in the observation group was 88.0%, higher than 60.0% in the control group (P < 0.05); After operation, the intrauterine adhesion score in the observation group was lower than that in the control group (P < 0.05).
he difference between sodium hyaluronate and hyaluronic acid. Hyaluronic acid is acid and sodium hyaluronate is salt. Sodium is more stable. Adding sodium will turn into a non-Newtonian fluid. It is very good for exfoliation. Hyaluronic acid is a holy tonic product. You should know that hyaluronic acid belongs to hyaluronic acid. Sodium hyaluronate has moisturizing effect. Hyaluronic acid is a biochemical drug with high clinical value. It is widely used in various ophthalmic operations, such as lens implantation, corneal transplantation and anti glaucoma surgery. It can also be used to treat Guan inflammation and accelerate wound healing.

Sodium hyaluronate has the following functions in skin beauty and moisturizing. Moisturizing effect is the most important role of sodium hyaluronate in cosmetics. Compared with other moisturizers, sodium hyaluronate has the highest moisture absorption in low humidity environment and the lowest moisture absorption in high humidity environment. This unique property can meet the requirements of skin for moisturizing effect of cosmetics in different seasons and environmental humidity. It has nutritional effect. Sodium hyaluronate is the inherent biological substance of human body. It is the supplement of endogenous hyaluronic acid through the supplement of exogenous sodium hyaluronate. Repair and prevention. Sodium hyaluronate can promote the proliferation and differentiation of epidermal cells, remove oxygen free radicals and regenerate the damaged skin. Lubricity and film formation. After sodium hyaluronate is applied to the skin, a film can be formed on the skin surface to make the skin have a good sense of smoothness and lubrication and protect the skin. Thickening. The aqueous solution of sodium hyaluronate 1% is gelatinous, and it can play a role of thickening and stabilization in cosmetics.

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Difference between sodium hyaluronate and hyaluronic acid

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