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Function and application of chondroitin sulfate

        Chondroitin sulfate is a very common drug in daily life. It refers to a class of glycosaminoglycans covalently linked to proteins to form proteoglycans. It can be used in combination with glucosamine. It has a significant effect on the treatment of joint diseases. At the same time, it also has multiple effects such as pain relief and promoting cartilage regeneration. Friends in need can have a try, But you need to pay attention to follow the doctor's advice. Chondroitin sulfate (CS) is a kind of glycosaminoglycan covalently linked to protein to form proteoglycan. Chondroitin sulfate is widely distributed in the extracellular matrix and cell surface of animal tissues. The sugar chain is composed of alternating glucuronic acid and N-acetylgalactosamine (also known as N-acetylgalactosamine) disaccharide units, which are connected to the serine residue of core protein through a sugar like link region. Chondroitin sulfate exists in all organisms except plants, from nematode to human, and plays many important physiological functions. Although the main chain structure of polysaccharide is not complex, it is highly heterogeneous in terms of the degree of sulfation, sulfate group and the distribution of the two differences to the re chain of isoglucuronic acid. The fine structure of chondroitin sulfate determines its functional specificity and interaction with many protein molecules.
Chondroitin sulfate
        Chondroitin sulfate's role and use, the main way of application in medicine is as a drug for the treatment of joint diseases, combined with glucosamine, with analgesic, promote cartilage regeneration effect, can fundamentally improve joint problems. It can absorb water into proteoglycan molecules, thicken cartilage and increase the amount of synovial fluid in joints. One of the important functions of chondroitin is to serve as a pipeline to deliver important oxygen supply and nutrients to the joints, help remove the waste in the joints, and remove carbon dioxide and waste at the same time. Since there is no blood supply to articular cartilage, all the oxygenation, nourishment and lubrication come from synovial fluid.
        Chondroitin sulfate has a protective effect on corneal collagen fibers, which can promote the growth of fibers in the matrix, enhance permeability, improve blood circulation, accelerate metabolism, promote the absorption of osmotic fluid and eliminate inflammation; Its polyanion has strong water retention, can improve the water metabolism of cornea tissue, has strong affinity for cornea, can form a layer of permeable water retaining film on the corneal surface, and improve the symptoms of dry eyes. By promoting the formation of stroma, providing a framework for the migration of cells, it is conducive to the migration of corneal epithelial cells, so as to promote the healing of corneal trauma, the absorption of exudate and the elimination of inflammation.
Chondroitin sulfate
        Through high-tech deep processing, it can treat nervous headache, trigeminal neuralgia, coronary heart disease, angina pectoris, myocardial hypoxia, cardiovascular and cerebrovascular diseases, arthralgia, atherosclerosis and hepatitis. CS also has anticoagulant and antithrombotic effects, It can also be used in the adjuvant treatment of hearing impairment and liver function damage caused by streptomycin and hyperlipidemia. It can be used as an additive in health products and food, and has the functions of strengthening human body constitution, anti bacteria and beauty. Improve hearing and dry skin. In vivo, it can inhibit the absorption of lipid and glucose in small intestine to achieve weight loss.